COMPOSITION:

Ceftiofur sodium        50mg

DESCRIPTION:

Powder and solvent for solution for injection. The reconstituted product is a clear brownish yellow to yellow solution containing 50 mg/ml ceftiofur (as sodium).

INDICATIONS:

Cattle:

- For the treatment of bacterial respiratory disease associated with Pasteurella multocida and Mannheimia haemolytica sensitive to ceftiofur.

- For the treatment of cattle with interdigital necrobacillosis (foot rot) in which Fusobacterium necrophorum and Bacteroides melaninogenicus (Porphyromonas asaccharolytica) sensitive to ceftiofur are involved.

Pigs:

- For the treatment of bacterial respiratory disease in which Pasteurella multocida, Actinobacillus pleuropneumonia and Streptococcus suis sensitive to ceftiofur are involved.

DOSAGE AND ADMINISTRATION:

Intramuscular use.

The solution for injection is to be reconstituted with 20 ml of water for injections for the 1 g presentation and with 80 ml of water for injections for the 4 g presentation.

Rapid addition of solvent will give best results.

Cattle:

- For respiratory disease

1 mg ceftiofur (as sodium) per kg bodyweight per day for 3 to 5 days, i.e. 1 ml of reconstituted solution per 50 kg bodyweight per day for 3 to 5 days.

- For interdigital necrobacillosis (foul in the foot rot)

1 mg ceftiofur (as sodium) per kg bodyweight per day for 3 days, i.e. 1 ml of reconstituted solution per 50 kg bodyweight per day for 3 days.

Pigs:

3 mg ceftiofur (as sodium) per kg bodyweight per day for 3 days, i.e. 1 ml of reconstituted solution per 16 kg bodyweight per day for 3 days.

The dose should be given once daily at 24 hour intervals.

Do not administer more than 10 ml per injection site.

CONTRAINDICATIONS:

Do not use in animals previously found to be hypersensitive to ceftiofur or other beta-lactamines.

ADVERSE EFFECTS:

Fleeting symptoms of pain may be observed at the injection site.

In local tolerance studies conducted in cattle and swine, mild and transient swelling were observed at the injection site in a few pigs 6 hours after injection. No signs of swelling at the injection site were observed 24 hours after injection.

Hypersensitivity reactions can occasionally occur. In the case of an allergic reaction, treatment should be stopped.