Liquid Injection

Title:

Doramectin Injection 1%

Type:Liquid Injection
Release Date:2017/11/24 16:46:04
Inquiry:

Composition

Each ml contains:

Doramectin..................................................10mg

Excipient......................................................q.s. 1ml

 

Dosage and Administration

This is a clear, sterile solution. In common with other non-aqueous formulations the product contains no antimicrobial preservative. Dry, sterile equipment and aseptic procedures should therefore be used when administering this product to animals. Swab the septum before removing the dose. When the temperature of the formulation is below 5°C, syringeability may be improved by gently warming the injecting equipment and product.

When treating individual animals syringes must be filled from the vial through a dry, sterile draw-off needle that has been placed in the vial stopper. Vial stoppers must not be broached more than 20 times.

 

For cattle:

Administer this solution at a dosage of 200 mcg doramectin per kilogram of bodyweight by the subcutaneous route. Each ml contains 10 mg of doramectin, sufficient to treat 50 kg of bodyweight. Each injection should be made into the neck region using a dry sterile 16 to 18 gauge needle, 15 mm in length.

 

For sheep:

For the treatment and control of Psoroptes ovis (sheep scab mite) and Nematodirus battus, a dosage of 300 mcg/kg bodyweight should be used by the intramuscular route. Each ml contains 10 mg of doramectin, 1.0 ml is sufficient to treat 33 kg of bodyweight

In adult sheep each intramuscular injection should be made using a dry sterile 16 to 18 gauge needle, 25 mm in length. (For the treatment of individual sheep a disposable 2 ml syringe calibrated in increments of 0.1 ml should be used).

Suggested dose rates for Psoroptes ovis (sheep scab mite) and Nematodirus battus: 1 ml/33 kg bodyweight (300 mcg/kg). Sheep over 16 kg bodyweight:

 

Bodyweight

Dose

17 - 25 kg

0.75 ml

26 - 33 kg

1.0 ml

34 - 41 kg

1.25 ml

42 - 50 kg

1.5 ml

51 - 58 kg

1.75 ml

59 - 66 kg

2.0 ml

67 - 74 kg

2.25 ml

75 - 83 kg

2.5 ml

84 - 91 kg

2.75 ml

92 - 99 kg

3.0 ml

In young lambs of less than 16 kg bodyweight seek veterinary advice regarding the use of appropriate sized needles and of 1 ml disposable syringes graduated in increments of 0.1 ml or less. Suggested dose rates at 1 ml/33 kg bodyweight (300 mcg/kg) in young lambs:

 

Bodyweight

Dose

Less than 4 kg

0.1 ml

5 - 6 kg

0.2 ml

7 - 10 kg

0.3 ml

11 - 13 kg

0.4 ml

14 - 16 kg

0.5 ml

For treatment of gastro-intestinal roundworms, lungworms and nasal bots, administer for injection once at a dosage of 200 mcg doramectin per kilogram of bodyweight by the intramuscular route. Each ml contains 10 mg of doramectin, sufficient to treat 50 kg of bodyweight

 

For pigs:

A single treatment of 0.3 ml (3 mg doramectin) per 10 kg bodyweight (1ml per 33 kg), equivalent to 300 μg/kg bodyweight, administered by intramuscular injection.

Piglets weighing 16 kg or less should be dosed in accordance with the following table:

 

Bodyweight (kg)

Dose (ml)

Less than 4kg

0.1 ml

5-7 kg

0.2 ml

8-10 kg

0.3 ml

11-13 kg

0.4 ml

14-16 kg

0.5 ml

 

 

Withdrawal time

Meat and offal: 56 days.

 

Storage

Store in cool and dry place, do not above 30°C. Protect from direct sunlight